Clozapine N-oxide (hydrochloride)
Catalogue number:
CAY25780-10 mg
Supplier:
Size:
10 mg
Product is available in:
£191.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2250025-93-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H19ClN4O • 2HCl
Molecular Weight:
415.7438
Alternative Names:
8-chloro-11-
Product Description:
A metabolite of clozapine and muscarinic DREADD agonist (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively); prevents action potential firing in cultured hippocampal neurons transiently expressing hM4D receptors; increases glutamate in the nucleus accumbens core and inhibits cue-induced reinstatement of cocaine-seeking behavior in rats transfected with hM3Dq DREADD receptors
