PF-6274484
Catalogue number:
CAY22698-10 mg
Supplier:
Size:
10 mg
Product is available in:
£210.00
Estimated delivery Mon 29 Sep
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1035638-91-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H14ClFN4O2
Molecular Weight:
372.8
Alternative Names:
n-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-2-propenamide
Product Description:
An EGFR inhibitor (IC50s = 0.18 and 0.14 nM for wild-type EGFR and inhibitor-resistant EGFRL858R/T790M, respectively); inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells (IC50s = 5.8 and 6.6 nM, respectively)
