2,3-Dimethoxy-5-methyl-p-benzoquinone
Catalogue number:
CAY20504-10 g
Supplier:
Size:
10 g
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
605-94-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C9H10O4
Molecular Weight:
182.2
Alternative Names:
2,3-dimethoxy-
Product Description:
An intermediate in the synthesis of ubiquinones that has anticancer activity; inhibits the growth of SKOV-3, A2780, and A2870/CP70 human ovarian carcinoma cells (IC50s = 26.6, 27.3, and 28.4 µM, respectively); halts the cell cycle at the G2/M phase, increases ROS production, and induces autophagy and apoptosis in SKOV-3 human ovarian carcinoma cells; downregulates the protooncogene HER-2 in vitro; decreases the incidence of tumors and tumor burden in a SKOV-3 mouse xenograft model at 2.5 mg/kg every four days
