Periplocin
Catalogue number:
CAY25216-50 mg
Supplier:
Size:
50 mg
Product is available in:
£1227.00
Estimated delivery Mon 22 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
13137-64-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C36H56O13
Molecular Weight:
696.82204
Alternative Names:
(3β,5β)-3-
Product Description:
A cardiac glycoside with anticancer activity; increases viability and proliferation of CMECs at 2-50 µM; improves left ventricular structure and function in a rat model of chronic heart failure; inhibits cell proliferation in nine lung cancer cell lines (IC50s = 0.12-53 µM); induces apoptosis in SGC-7901 and MGC-803 gastric cancer cells and activates the ERK1/2-EGR1 pathway; reduces tumor growth in an HCC mouse xenograft model at 5 and 20 mg/kg; inhibits tumor growth in an A549 lung cancer mouse xenograft model at 50 and 100 µg
