AF-DX 384
Catalogue number:
CAY25638-5 mg
Supplier:
Size:
5 mg
Product is available in:
£113.00
Estimated delivery Tue 30 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
118290-26-9
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C27H38N6O2
Molecular Weight:
478.6
Alternative Names:
n-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11h-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
- MSDS: View or download
Product Description:
An M2 and M4 muscarinic acetylcholine receptor antagonist (Kis = 6.03 and 10 nM, respectively); selective for M2 and M4 over M1, M3, and M5 receptors (Kis = 30.9, 66.07, and 537.03 nM, respectively); increases acetylcholine release in the hippocampus and cortex of young and aged rats in vivo following local infusion at 1 µM and in the cortex at 5 mg/kg, i.p.; reverses deficits in novel object recognition and passive avoidance in aged rats, as well as scopolamine-induced deficits in young rats
