3CAI
Catalogue number:
CAY14303-250 mg
Supplier:
Size:
250 mg
Product is available in:
£131.00
Estimated delivery Fri 9 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
28755-03-5
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C10H8ClNO
Molecular Weight:
193.6
Alternative Names:
2-chloro-1-
Product Description:
An inhibitor of Akt1 and Akt2 with anticancer activity; inhibits Akt1 and Akt2 in a kinase assay, but has no effect on MEK1, JNK1, ERK1, or PBK at 1 µM; increases apoptosis in HCT116 and HT-29 colon cancer cells at 4 µM; inhibits growth of HCT116 cells in vitro; reduces tumor growth in an HCT116 mouse xenograft model at 30 mg/kg; decreases status epilepticus-induced vasogenic edema and reduces increases in eNOS levels in the piriform cortex in rats at 25 µM
