3CAI
Catalogue number:
CAY14303-250 mg
Supplier:
Size:
250 mg
Product is available in:
£131.00
Estimated delivery Fri 30 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
28755-03-5
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C10H8ClNO
Molecular Weight:
193.6
Alternative Names:
2-chloro-1-
Product Description:
An inhibitor of Akt1 and Akt2 with anticancer activity; inhibits Akt1 and Akt2 in a kinase assay, but has no effect on MEK1, JNK1, ERK1, or PBK at 1 µM; increases apoptosis in HCT116 and HT-29 colon cancer cells at 4 µM; inhibits growth of HCT116 cells in vitro; reduces tumor growth in an HCT116 mouse xenograft model at 30 mg/kg; decreases status epilepticus-induced vasogenic edema and reduces increases in eNOS levels in the piriform cortex in rats at 25 µM
