Aconine
Catalogue number:
CAY25048-10 mg
Supplier:
Size:
10 mg
Product is available in:
£487.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
509-20-6
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C25H41NO9
Molecular Weight:
499.6
Alternative Names:
(1α,3α,6α,14α,
Product Description:
An active metabolite of aconitine; inhibits osteoclast differentiation of RANKL-stimulated RAW 264.7 cells and bone resorption in a pit formation assay; inhibits RANKL-induced activation of NF-κB and NFATc1 in RAW 264.7 cells; toxic to mice at 120 mg/kg; induces flaccid paralysis and toxicity in rats (TD50 = 1.5 µmol/animal; LD50 = 1.7 µmol/animal)
