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Nonivamide

Catalogue number:
CAY25328-5 g
Supplier:
Size:
5 g
Product is available in:
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£167.00 Estimated delivery Fri 19 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2444-46-4

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C17H27NO3

Molecular Weight:

293.40122

Alternative Names:

n-[(4-hydroxy-3-methoxyphenyl)methyl]nonanamide, nonanoic acid vanillylamide, nsc 172795, n-vanillylnonanamide, n-vanillylpelargonamide, pelargonic acid vanillylamide, pseudocapsaicin

Product Description:

A TRPV1 agonist; toxic to NHBE, BEAS-2B, and TRPV1-OE cells (LC50s = 160, 115, and 1 µM, respectively); increases calcium flux in TRPV1-OE cells (EC50 = 1.4 µM); increases GADD153 mRNA expression by 7- and 6-fold at 2 and 20 µM, respectively; increases the release of dopamine and serotonin from SH-SY5Y cells in a calcium-dependent and TRPV1-independent manner at 1 µM; reduces respiration and is toxic to mice (LD50s = 200 and 413 mg/kg for oral and inhaled administration, respectively)

CAY25328-5 g: Nonivamide
CAY25328-5 g: Nonivamide