3,5-Dicaffeoylquinic Acid
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2450-53-5
≥95%
A crystalline solid
C25H24O12
516.45086
(1α,3r,4α,5r)-
- MSDS: View or download
A natural phenolic compound that has antioxidant, anti-inflammatory, and antiviral biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 71.8 µM); inhibits superoxide production in fMLF- and cytochalasin B-activated human neutrophils (IC50 = 1.92 µM); inhibits HIV-1 integrase 3’-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 µg/ml, respectively); inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 µg/ml); protects mice from LPS-induced acute lung injury and decreases neutrophil count in BALF at 25 mg/kg
