TPMPA (hydrate)
Catalogue number:
CAY24302-5 mg
Supplier:
Size:
5 mg
Product is available in:
£167.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C6H12NO2P • XH2O
Molecular Weight:
161.138781
Alternative Names:
p-methyl-p-
- MSDS: View or download
Product Description:
A selective GABAA-ρ1 (ρ1 GABAC) receptor antagonist (Kbs = 2 and 16 µM for GABAA-ρ1 over GABAA-ρ2, respectively); blocks the inhibitory effect of 3-APMPA on EPSCs in rat hippocampal slices (EC50 = 490 µM); increases light sensitivity and the maximal response of rat retinal ganglion cells without altering their dynamic range (100 µM); increases waking from 45 to 62% compared to vehicle control and decreases slow-wave and REM by 11 and 5.4%, respectively, in rats (50 µg, i.c.v.)
