PHT-427
Catalogue number:
CAY24188-5 mg
Supplier:
Size:
5 mg
Product is available in:
£49.00
Estimated delivery Mon 8 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1191951-57-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C20H31N3O2S2
Molecular Weight:
409.61116
Alternative Names:
4-dodecyl-n-
- MSDS: View or download
Product Description:
An inhibitor of Akt and PDPK1 (Ki = 2.7 and 5.2 µM, respectively); binds to the pleckstrin homology binding domain; inhibits PDPK1 and Akt autophosphorylation in BxPC-3 prostate cancer cells (10 µM); reduces tumor growth in BxPC-3, Panc-1, MiaPaCa-2, PC3, SKOV3, A549, and MCF-7 xenograft mouse models (125-250 mg/kg); enhances the antitumor effect of paclitaxel in an MCF-7 breast cancer xenograft mouse model
