ML RR-S2 CDA (ammonium salt)
Catalogue number:
CAY24106-500 ug
Supplier:
Size:
500 µg
This product is no longer available to order.
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1638750-96-5
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C20H22N10O10P2S2 • 2NH4
Molecular Weight:
724.6
Alternative Names:
[p(r)]-5'-o-[(r)-hydroxymercaptophosphinyl]-p-thioadenylyl-(2'→5')-adenosine, cyclic nucleotide, diammonium salt, sting inducer-1
- Data sheet: View or download
- MSDS: View or download
Product Description:
An activator of STING; induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine BMMs isolated from wild-type, but not STING-/-, mice; induces IFN-β expression in PBMCs isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles; initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 murine mammary and CT26 murine colon cancer models
