ML RR-S2 CDA (ammonium salt)
Catalogue number:
CAY24106-1 mg
Supplier:
Size:
1 mg
Product is available in:
£213.00
Estimated delivery Wed 24 Sep
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1638750-96-5
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C20H22N10O10P2S2 • 2NH4
Molecular Weight:
724.606602
Alternative Names:
[p(r)]-5'-o-[(r)-hydroxymercaptophosphinyl]-p-thioadenylyl-(2'→5')-adenosine, cyclic nucleotide, diammonium salt, sting inducer-1
Product Description:
An activator of STING; induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine BMMs isolated from wild-type, but not STING-/-, mice; induces IFN-β expression in PBMCs isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles; initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 murine mammary and CT26 murine colon cancer models
