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CAS Number:
129414-88-6
Alternative Names:
4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-phenol
Product Description:
An Hsp27 and microtubule inhibitor; inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner; inhibits PKC phosphorylation of Hsp27; induces HCT116 cell cycle arrest in the G2/M phase via formation of the Mad2/p55CDC inhibitory complex and Bax activation of apoptosis; inhibits microtubule polymerization in HCT116 cells; reduces tumor volume in an HCT116 mouse xenograft model (50-100 mg/kg)
