This product is no longer available to order.
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
129414-88-6
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C19H19NO4
Molecular Weight:
325.4
Alternative Names:
4-ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]-phenol
- Data sheet: View or download
- MSDS: View or download
Product Description:
An Hsp27 and microtubule inhibitor; inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner; inhibits PKC phosphorylation of Hsp27; induces HCT116 cell cycle arrest in the G2/M phase via formation of the Mad2/p55CDC inhibitory complex and Bax activation of apoptosis; inhibits microtubule polymerization in HCT116 cells; reduces tumor volume in an HCT116 mouse xenograft model (50-100 mg/kg)
