Hydroxyurea
Catalogue number:
CAY23725-10 g
Supplier:
Size:
10 g
Product is available in:
POA
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This product is for research use only and is not for human consumption or therapeutic use.
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CAS Number:
127-07-1
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
CH4N2O2
Molecular Weight:
76.1
Alternative Names:
n-hydroxy-
Product Description:
An antineoplastic agent; inhibits DNA replication and cell proliferation and induces cell cycle arrest in the G1/S phase; inhibits proliferation of NCI H460 human lung cancer cells in vitro (IC50 = 0.56 mM); reduces RNR activity by 75% when used at a concentration of 5 mM via degradation of its active site tyrosyl radical; reduces leukocyte adhesion and extravasation in a humanized mouse model of SCD via NO production and a cGMP-dependent pathway; inhibits HIV-1 viral replication in PBMCs (IC90 = 0.4 mM)
