AL 082D06
Catalogue number:
CAY23455-1 mg
Supplier:
Size:
1 mg
Product is available in:
£62.00
Estimated delivery Wed 18 Feb
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
256925-03-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C23H24ClN3O2
Molecular Weight:
409.9
Alternative Names:
4,4'-[(2-
- MSDS: View or download
Product Description:
A non-steroidal glucocorticoid receptor antagonist; selective for GR over the androgen, progesterone, mineralocorticoid, and estrogen receptors (Kis = >4, >3, >3, and >10 µM, respectively; inhibits glucocorticoid-induced transcription and reverses dexamethasone-mediated repression of gene expression; inhibits DNA binding in vitro and in vivo; GR bound to AL 082D06 does not compete with a constitutively active GR
