Cilengitide (trifluoroacetate salt)
Catalogue number:
CAY22289-25 mg
Supplier:
Size:
25 mg
Product is available in:
£652.00
Estimated delivery Fri 14 Nov
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
199807-35-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C27H40N8O7 • CF3COOH
Molecular Weight:
702.679569
Alternative Names:
cyclo(l-arginylglycyl-l-α-aspartyl-d-phenylalanyl-n-methyl-l-valyl), trifluoroacetate salt, emd 121974
Product Description:
An integrin αVβ3 receptor antagonist; inhibits adhesion and induces apoptosis of U87MG and U373MG, but not U251MG cells that lack the integrin αVβ3 receptor, in vitro at a concentration of 20 µg/ml; delays tumor implantation time, reduces tumor growth, and prolongs survival in a U87MG mouse model of glioblastoma when administered at a dose of 200 µg/animal per day
