www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Polmacoxib

Catalogue number:
CAY17509-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£315.00 Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

301692-76-2

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C18H16FNO4S

Molecular Weight:

361.4

Alternative Names:

4-[3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl]-benzenesulfonamide

Product Description:

An inhibitor of COX-2 and carbonic anhydrase; inhibits COX-2 (IC50 = 40 nM in the absence of CAII) with lower inhibition in the presence of a CAII; prevents prostaglandin E2 (PGE2) production by >95 and 90% in HCA-7 and HT-29 human colon cancer cells, respectively (0.01 and 0.001 µg/ml); inhibits polyp formation and tumor growth (7 mg/kg)

CAY17509-5 mg: Polmacoxib
CAY17509-5 mg: Polmacoxib