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CAS Number:
19728-88-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C20H24N2S2 • C4H4O4
Molecular Weight:
28509
Alternative Names:
1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl-piperazine, (2z)-butenedioate, metitepine
Product Description:
A non-selective 5-HT receptor antagonist; potent antagonist of 5-HT1A and 5-HT1B (IC50 = 16 nM and Ki = 0.2 nM, respectively); potent antagonist of 5-HT2A, 5-HT2B, and 5-HT2C receptors (Kis = 3.16, 2.08, and 4.46 nM, respectively); binds to 5-HT5A, 5-HT5B, 5-HT6, and 5-HT7 receptors (Kds = 100, 15.8, 1.8, and 1 nM, respectively); has been used to characterize the role of serotonin in various biological processes
