TBPB
Catalogue number:
CAY22943-10 mg
Supplier:
Size:
10 mg
Product is available in:
£228.00
Estimated delivery Wed 20 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
634616-95-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C25H32N4O
Molecular Weight:
404.6
Alternative Names:
1,3-dihydro-
Product Description:
An allosteric agonist of M1 mAChRs (EC50 = 158 nM in CHO-K1 cells expressing rat recombinant receptors); selective for M1 over M2-5 receptors at concentrations up to 10 µM; potentiates NMDA-evoked currents in CA1 pyramidal cells at 3 µM; increases production of the non-amyloidogenic APP cleavage products APPsα and CTFα in PC12 cells overexpressing the human M1 receptor and APP at 1 µM; decreases amphetamine-induced hyperlocomotion in in a rat model that is predictive of antipsychotic-like activity
