LDN-0212320
Catalogue number:
CAY21650-10 mg
Supplier:
Size:
10 mg
Product is available in:
£152.00
Estimated delivery Wed 20 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
894002-50-7
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C17H15N3S
Molecular Weight:
293.4
Alternative Names:
3-[[(2-methyl
- MSDS: View or download
Product Description:
An activator of EAAT2; increases expression of EAAT2 in PA-EAAT2 cells (EC50 = 1.83 µM); selectively increases EAAT2 protein levels over EAAT1 and EAAT3 protein levels and increases glutamate uptake in primary dissociated neuron and astrocyte mixed cultures from 1-3 µM; decreases neuronal loss and degeneration in primary dissociated neuron and astrocyte mixed cultures at 3 µM; increases EAAT2 protein levels and glutamate uptake in mouse forebrain at 40 mg/kg; delays motor function decline and increases lifespan in the SOD1G93A transgenic mouse model of ALS
