Cathepsin L Inhibitor
Catalogue number:
CAY23249-25 mg
Supplier:
Size:
25 mg
Product is available in:
£635.00
Estimated delivery Fri 5 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
167498-29-5
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C26H26N2O5
Molecular Weight:
446.5
Alternative Names:
n-[(1s)-2-
- MSDS: View or download
Product Description:
A potent cathepsin L inhibitor (IC50 = 0.85 nM); selective for cathepsin L over calpain II and cathepsin B (IC50s = 184, and 85.1 nM, respectively); trypanocidal against T. brucei (ED50 = 45 nM); completely suppresses osteoclastic pit formation on femur slices isolated from bovine cortical bone at a concentration of 1 µg/ml; inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner
