SLC5111312 (hydrochloride)
Catalogue number:
CAY23288-1 mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1870811-01-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C22H27N5O3 • HCl
Molecular Weight:
445.94232
Alternative Names:
(2s,3s)-3-
- MSDS: View or download
Product Description:
A dual SPHK1 and SPHK2 inhibitor (Kis = 0.73 and 0.9 µM, respectively, using human recombinant kinases); selective for Sphk2 over Sphk1 in mice (Kis = 1 and 20 µM, respectively); not selective in rat (Kis = 1.1 and 0.8 µM for Sphk2 and Sphk1, respectively); decreases S1P in vitro at concentrations of 0.1 and 0.3 µM; decreases S1P in Sphk1-/- knockout mice and in rat at a dose of 10 mg/kg
