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AG-555

Catalogue number:
CAY23247-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£108.00 Estimated delivery Wed 17 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

133550-34-2

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C19H18N2O3

Molecular Weight:

322.4

Alternative Names:

(2e)-2-cyano-3-(3,4-dihydroxyphenyl)-n-(3-phenylpropyl)-2-propenamide, tyrphostin ag-555, tyrphostin b46

Product Description:

A tyrphostin EGFR inhibitor (IC50 = 0.7 µM); selectively inhibits EFGR over ErbB2 (IC50 = 35 µM); inhibits EGF-dependent growth of HER 14 cells (IC50 = 2.5 µM) as well as the growth of psoriatic keratinocytes isolated from patients with psoriasis from 1-50 µM; inhibits Mo-MuLV reverse transcriptase activity (IC50 = 10.8 µM) without affecting Mo-MuLV-infected NIH3T3 cell growth (IC50 = 210 µM)

CAY23247-10 mg: AG-555
CAY23247-10 mg: AG-555