Annonacin
Catalogue number:
CAY22415-500 ug
Supplier:
Size:
500 µg
Product is available in:
£181.00
Estimated delivery Thu 30 Jul
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
16622941-85-8
Purity:
≥90%
Formulation:
A solid
Molecular Formula:
C35H64O7
Molecular Weight:
596.9
Alternative Names:
5-methyl-3-[2,8,13-trihydroxy-13-[tetrahydro-5-(1-hydroxytridecyl)-2-furanyl]tridecyl]-2(5h)-furanone
- MSDS: View or download
Product Description:
A mitochondrial complex I inhibitor from A. muricata (IC50 = 54.8 nM); induces ATP depletion, tau pathologies, and dopaminergic cell death in rats (EC50s = 134, 44.1, and 60.8 nM, respectively); reduces cell survival (ED50 = 0.31 µM in MCF-7 cells); decreases MCF-7 xenograft tumor size in nude mice at a dose of 50 mg/kg per day
