Annonacin
Catalogue number:
CAY22415-500 ug
Supplier:
Size:
500 µg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
16622941-85-8
Purity:
≥90%
Formulation:
A solid
Molecular Formula:
C35H64O7
Molecular Weight:
596.9
Alternative Names:
5-methyl-3-
- MSDS: View or download
Product Description:
A mitochondrial complex I inhibitor from A. muricata (IC50 = 54.8 nM); induces ATP depletion, tau pathologies, and dopaminergic cell death in rats (EC50s = 134, 44.1, and 60.8 nM, respectively); reduces cell survival (ED50 = 0.31 µM in MCF-7 cells); decreases MCF-7 xenograft tumor size in nude mice at a dose of 50 mg/kg per day
