L-Allylglycine
Catalogue number:
CAY23348-5 g
Supplier:
Size:
5 g
Product is available in:
£1014.00
Estimated delivery Mon 22 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
16338-48-0
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C5H9NO2
Molecular Weight:
115.1
Alternative Names:
2s-amino-4-pentenoic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
A GAD inhibitor; reduces GAD activity by 60% when administered at a dose of 39.8 µmol/g per hour ex vivo in mouse brain preparations; i.p. administration (1.2 mmol/kg) induces convulsions and decreases GABA concentration throughout the cerebellum, pons, medulla, striatum, cortex, and hippocampus in mice; chronic administration (3.2 µg/0.5 µl per hour for 13 days) increases locomotor activity in an open field test and impairs attention in the 5-choice serial reaction time task (5CSRTT); inhibits GAD in vitro only when used at high concentrations (1-80 mM)
