HDAC3 Inhibitor
Catalogue number:
CAY21057-5 mg
Supplier:
Size:
5 mg
Product is available in:
£274.00
Estimated delivery Thu 18 Sep
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2044701-99-5
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C20H23N3O2
Molecular Weight:
337.4
Alternative Names:
4-[[[(2e)-1-oxo-3-phenyl-2-propen-1-yl]amino]methyl]-benzoic acid 2-propylhydrazide, histone deacetylase 3
Product Description:
An allosteric HDAC3 inhibitor (Ki = 0.16 nM); selective for HDAC3 over HDAC1 and HDAC2 (IC50s = 0.95, 11.81, and 95.45 nM, respectively, using recombinant HDACs; selective for acute myeloid, monocytic, and lymphoblastic leukemia cell lines (EC50s = 36.37, 76.64, and 151.7 nM, respectively) over chronic myeloid, acute promyelocytic, and acute lymphoblastic cells (EC50s = 2,160, >10,000, and >10,000 nM, respectively)
