Amsacrine (hydrochloride)
Catalogue number:
CAY22223-10 mg
Supplier:
Size:
10 mg
Product is available in:
£92.00
Estimated delivery Mon 6 Jul
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
54301-15-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H19N3O3S • HCl
Molecular Weight:
429.9
Alternative Names:
n-[4-(9-
Product Description:
A topoisomerase II poison; stimulates formation of a complex between DNA and topoisomerase II in which the DNA is cleaved and topoisomerase II remains covalently linked to the 5’ end of the DNA cleavage products; inhibits the DNA strand-passing activity of topoisomerase II at a concentration of 20 µg/ml; reduces growth of LoVo human colorrectal carcinoma and T1 human lymphoma cells in a dose-dependent manner; antitumor activity against several murine leukemia, melanoma, lung, colon, and mammary xenograft mouse models
