Rutaecarpine
Catalogue number:
CAY22897-5 mg
Supplier:
Size:
5 mg
Product is available in:
£69.00
Estimated delivery Thu 4 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
84-26-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H13N3O
Molecular Weight:
287.3
Alternative Names:
8,13-dihydro-
- MSDS: View or download
Product Description:
A quinazolinone alkaloid with diverse biological activities; inhibits COX-1 and COX-2 in BMMC cells (IC50s = 8.7 and 0.28 µM, respectively); selective for COX-2 in HEK293 cells (IC50s = >400 and 2.8 µM, for COX-1 and COX-2, respectively); slows cancer cell growth in vitro (GI50s = 8.41-31.6 µM); induces vasodilation (0.1-10 µM) in isolated rat aorta; decreases plasma levels of caffeine in rat through CYP1A2 and CYP2E1 metabolism induction at a dose of 80 mg/kg
