TRX-818 (sodium salt)
Catalogue number:
CAY22209-5 mg
Supplier:
Size:
5 mg
Product is available in:
£232.00
Estimated delivery Wed 7 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1256037-62-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C16H11FNO6P • 2Na
Molecular Weight:
409.213384
Alternative Names:
2-(3-fluorophenyl)
Product Description:
An anticancer compound; inhibits vasculogenic mimicry network formation in C8161 and SK-MEL-28 melanoma cells from ≤5-10 nM; decreases pro-Nodal protein levels and Smad2 phosphorylation in C8161 cells at 10 nM; reduces tumor volume (MED = 50 mg/kg) and decreases the number of vasculogenic mimicry channels in tumors at 100 mg/kg in an HCT116 colon cancer mouse xenograft model; reduces tumor growth in a Hep3B mouse xenograft model in a dose-dependent manner at 7.5, 15, and 30 mg/kg
