(±)14-HDHA

Name: (±)14-HDHA
Brand: Cayman Chemical
SKU: CBSKU_100703272
Price: 381 GBP
Availability: InStock

Catalogue number:

Add to favourites

CAY33550-100 ug

Supplier:

Cayman Chemical

Size:

100 µg

Product is available in:

Currency:
GBP
EUR

£381.00

add to basket

Estimated delivery Fri 9 Jan
Shipping is calculated in checkout

This product is for research use only and is not for human consumption or therapeutic use.

CAS Number:

87042-40-8

Purity:

≥98%

Formulation:

A 100 µg/ml solution in ethanol

Molecular Formula:

C22H32O3

Molecular Weight:

344.5

Alternative Names:

(±)14-hydroxy-4z,7z,10z,12e,16z,19z-docosahexaenoic acid, (±)14-hdohe, 14-hydroxy docosahexaenoic acid

Product Description:

(±)14-HDHA is an autoxidation product of DHA in vitro.{7479,7491} It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.{7480,7490,7492} DHA is metabolized to 14(S)-HDHA by human platelets along with 11(S)-HDHA.{7483,7484,7492} 14(S)-HDHA is also produced by salmon gills upon stimulation with calcium ionophore.{7514} 14(S)-HDHA is an inhibitor of U-46619-induced human platelet aggregation and rabbit and rat aortic smooth muscle contraction with IC50 values of about 70, 3.6, and 5.3 µM, respectively.{7484,7481} (±)14-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant PUFA.