Napabucasin
Catalogue number:
CAY22255-50 mg
Supplier:
Size:
50 mg
Product is available in:
£635.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
83280-65-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C14H8O4
Molecular Weight:
240.2
Alternative Names:
2-acetyl-
Product Description:
An inhibitor of cancer cell stemness; reduces growth in a panel of cancer cells enriched for high stemness (IC50s = 0.291-1.249 µM); decreases protein and gene expression of various self-renewal and pro-survival markers in FaDu HNSCC cells; inhibits tumor growth in a PaCa-2 mouse xenograft model and prevents tumor regrowth after cessation of treatment (20 mg/kg per day); blocks formation of spleen and liver metastases in an HT29 ISMS model; reduces tumor volume in PC3 and 22RV1 prostate cancer mouse xenograft models (40 mg/kg)
