£42.00
Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
448947-81-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C13H8Cl2N4S2
Molecular Weight:
355.3
Alternative Names:
2-[5-[[(2,6-
Product Description:
A Piezo1 channel agonist (EC50s = 17.1 and 26.6 µM for murine and human Piezo1-transfected HEK293T cells, respectively); selective for Piezo1 as it elicits Ca2+ flux in Piezo1- but not Piezo2-transfected HEK293T cells; slows the inactivation phase of murine Piezo1 transient currents and sensitizes them to activation by mechanical pressure; induces dehydration and a change in shape of wild-type red blood cells but not Piezo1 knockout cells
