JNJ-42756493
Catalogue number:
CAY21813-25 mg
Supplier:
Size:
25 mg
Product is available in:
£341.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1346242-81-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C25H30N6O2
Molecular Weight:
446.6
Alternative Names:
n1-(3,5-di
Product Description:
A pan-FGFR inhibitor (IC50s = 1.2, 2.5, 3, and 5.7 nM for FGFR1, -2, -3, and -4, respectively); selective for FGFRs over VEGFR2 (IC50 = 36.8 nM); inhibits the proliferation of Ba/F3 cells expressing FGFR1, 3, or 4 (IC50s = 22.1, 13.2, and 25 nM, respectively); reduces tumor growth in a SNU-16 gastric cancer mouse xenograft model at 10 and 30 mg/kg
