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GNE-3511

Catalogue number:
CAY19174-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
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£651.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1496581-76-0

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C23H26F2N6O

Molecular Weight:

440.5

Alternative Names:

2-[[6-(3,3-difluoro-1-pyrrolidinyl)-4-[1-(3-oxetanyl)-4-piperidinyl]-2-pyridinyl]amino]-4-pyridinecarbonitrile

Product Description:

A selective and highly potent inhibitor of DLK; also inhibits phosphorylated JNK (IC50 = 30 nM); selective over other MAP kinases, JNKs, and MLKs; protects primary neurons in an in vitro axon degeneration assay (IC50 = 107 nM); decreases p-c-Jun expression in a mouse MPTP model of Parkinson’s disease

CAY19174-25 mg: GNE-3511
CAY19174-25 mg: GNE-3511