Etrasimod
Catalogue number:
CAY21661-25 mg
Supplier:
Size:
25 mg
Product is available in:
£876.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1206123-37-6
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C26H26F3NO3
Molecular Weight:
457.5
Alternative Names:
(3r)-7-[[4-
Product Description:
A potent S1P receptor antagonist (EC50s = 0.093, 0.44, 0.32, 0.34, and 0.32 nM for human, mouse, rat, dog, and monkey S1P1 receptors); selective for S1P1, S1P4, and S1P5 receptors (EC50 = 6.1, >10,000, >10,000, 147, and 24.4 nM for S1P1-5, respectively); decreases peripheral lymphocytes in mouse, rat, dog, and monkey (IC50s = 101, 51, 58, and 98 nM, respectively) when administered at a dose of 1 mg/kg, i.v.; delays or prevents the onset and severity of murine EAE at doses of 0.3, 1, or 3 mg/kg
