PI3-Kinase α Inhibitor 2 (hydrochloride)
Catalogue number:
CAY21197-1 mg
Supplier:
Size:
1 mg
Product is available in:
£93.00
Estimated delivery Wed 24 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1188890-32-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C16H15N3O2S • 2HCl
Molecular Weight:
386.3
Alternative Names:
3-[4-(4-morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol, dihydrochloride, phosphatidylinositol 3-kinase α inhibitor 2, pi3kα inhibitor 2
Product Description:
An inhibitor of PI3K p110α (IC50 = 2 nM in an enzyme assay); selective for p110α over p110β, p110γ, and PI3K C2β (IC50s = 16, 660, and 220 nM, respectively); inhibits mTOR (IC50 = 49 nM); inhibits proliferation in A375 melanoma cells (IC50 = 0.58 µM)
