BGC 20-1531 (hydrochloride)
Catalogue number:
CAY19742-500 ug
Supplier:
Size:
500 µg
Product is available in:
£46.00
Estimated delivery Thu 6 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1962928-26-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C26H24N2O6S • HCl
Molecular Weight:
529
Alternative Names:
4-[[4-(5-methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-n-[(2-methylphenyl)sulfonyl]-2-furancarboxamide, monohydrochloride, pgn 1531
Product Description:
A potent and selective EP4 receptor antagonist (Kis = 11.7, >10,000, and >10,000 nM for EP4, EP2, and EP3, respectively); selective for EP4, exhibiting 2-induced cAMP accumulation in HEK293 EBNA cells that stably express human EP4 receptors; reverses PGE2-induced vasorelaxation (Kb = 15.85 nM) in human middle cerebral and middle meningeal arterial rings; prevents PGE2-induced increases in carotid blood flow and decreases in carotid resistance in dogs (ID50 = 5 mg/kg)
