5'-Ethynyl-2'-deoxycytidine
Catalogue number:
CAY11581-1 mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
69075-47-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C11H13N3O4
Molecular Weight:
251.2
Alternative Names:
2'-deoxy-5-
Product Description:
A nucleoside analog; inhibits replications of HSV-1 KOS strain (ID50 = 0.2 µg/mL); reduces virus-induced cytopathogenicity of HSV-1, HSV-2, and vaccinia virus strains in PRK cells (MICs = 0.2-0.4, 1-2, and 5 µg/ml, respectively); selectively inhibits thymidylate synthetase (ID50s = 3 and 120 µg/ml for incorporation of [1',2'-3H]deoxyuridine and [CH3-3H]deoxythymidine, respectively); has been used to monitor DNA synthesis and cellular replication via click chemistry conjugation to fluorochromes
