Nisoldipine
Catalogue number:
CAY20998-500 mg
Supplier:
Size:
500 mg
Product is available in:
£127.00
Estimated delivery Tue 16 Sep
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
63675-72-9
Purity:
≥97%
Formulation:
A crystalline solid
Molecular Formula:
C20H24N2O6
Molecular Weight:
388.4
Alternative Names:
1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-methyl 5-(2-methylpropyl) ester, (±)-bay-k-5552, (±)-nisoldipine
Product Description:
A calcium channel inhibitor; binds to calcium channels in isolated rat ventricular membranes (Kd = 0.04 nM) and inhibits calcium uptake by smooth muscle cells; reduces ventricular tachycardia and fibrillization and increases survival in a rat model of ventricular arrhythmias induced by myocardial ischemia at 3 mg/kg; dietary administration reduces reduces systolic blood pressure in spontaneously hypertensive rats at 50 and 100 mg/kg
