AMG 319
Catalogue number:
CAY17383-5 mg
Supplier:
Size:
5 mg
Product is available in:
£194.00
Estimated delivery Wed 10 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1608125-21-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H16FN7
Molecular Weight:
385.4
Alternative Names:
7-fluoro-αs-
Product Description:
A potent, selective inhibitor of PI3Kδ (IC50 = 18 nM); blocks anti-IgM/CD40L-induced proliferation (IC50 = 8.6 nM) and reduces Akt phosphorylation (IC50 = 1.5 nM) in B cells; reduces inflammation in two animal models
