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AN3365 (hydrochloride)

Catalogue number:
CAY20572-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
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£52.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1234563-16-6

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C11H16BNO4 • HCl

Molecular Weight:

273.5

Alternative Names:

3-[[(3s)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl]oxy]-1-propanol, monohydrochloride, epetraborole, gsk2251052

Product Description:

A LeuRS inhibitor (IC50 = 0.31 µM for the E. coli enzyme); active against a variety of bacteria, including MDR clinical isolates (MICs = 2-8 µg/ml); inhibits protein, RNA, DNA, and fatty acid synthesis in E. coli (IC50s = 8.3, 105, 366, and 396 µg/ml, respectively); reduces the number of CFUs in neutropenic mouse thigh models of E. coli or P. aeruginosa infection at 30 mg/kg

CAY20572-1 mg: AN3365 (hydrochloride)
CAY20572-1 mg: AN3365 (hydrochloride)