Methoxy-X04

A fluorescent probe for Aβ; used to detect and quantify plaques, tangles, and cerebrovascular amyloid; high in vitro binding affinity (Ki = 26.8 nM) for fibrillar β-sheet deposits; used for in vivo imaging in APP/PS1 mice; displays an excitation peak at 750 nm with emission between 460 and 500 nm