E7046
Catalogue number:
CAY19673-10 mg
Supplier:
Size:
10 mg
Product is available in:
£118.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1369489-71-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C22H18F5N3O4
Molecular Weight:
483.4
Alternative Names:
4-[(1s)-1-
Product Description:
An EP4 receptor antagonist (IC50 = 13.5 nM); inhibits PGE2-induced activation of pro-tumor type 2 macrophages and prevents PGE2-induced suppression of T cell proliferation in isolated human PBMCs from 0.1-3 µM; reduces tumor volume in Panc02 murine pancreatic and EMT6 murine breast cancer models at 5, 50, and 100 mg/kg
