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GSK481

Catalogue number:
CAY20308-25 mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
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  • Rest of World
£743.00 Estimated delivery Tue 12 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1622849-58-4

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C21H19N3O4

Molecular Weight:

377.4

Alternative Names:

5-(phenylmethyl)-n-[(3s)-2,3,4,5-tetrahydro-5-methyl-4-oxo-1,5-benzoxazepin-3-yl]-3-isoxazolecarboxamide

Product Description:

A selective inhibitor of RIP1 that blocks autophosphorylation of Ser166 on wild-type human RIP1 with an IC50 value of 2.8 nM; inhibits RIP1 from human and cynomolgus monkey but is at least 100-fold less potent against non-primate RIP1

CAY20308-25 mg: GSK481
CAY20308-25 mg: GSK481