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Esculetin

Catalogue number:
CAY19286-1 g
Supplier:
Size:
1 g
Product is available in:
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£41.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

305-01-1

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C9H6O4

Molecular Weight:

178.1

Alternative Names:

6,7-dihydroxy-2h-1-benzopyran-2-one, 6,7-dihydroxycoumarin, aesculetin, cichorigenin, nsc 26427

Product Description:

A coumarin with diverse biological activities; inhibits 5-LO and 12-LO (IC50s = 4 and 2.5 µM, respectively), as well as JARID1B (IC50 = 4.6 µM); active against B. cereus, S. lutea, S. aureus, S. lactis, A. faecalis, and E. coli; reduces LRRK2G2019S-induced production of hydrogen peroxide in Drosophila brain lysates and decreases cell death in LRRK2G2019S-expressing primary human cortical neurons; reduces croton oil-induced ear edema in mice at 1.68 µmol/ear; inhibits acetylcholine-induced writhing in mice (ED50 = 69 mg/kg)

CAY19286-1 g: Esculetin
CAY19286-1 g: Esculetin