VPS34-IN-1
Catalogue number:
CAY17392-10 mg
Supplier:
Size:
10 mg
Product is available in:
£208.00
Estimated delivery Fri 8 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1383716-33-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C21H24ClN7O
Molecular Weight:
425.9
Alternative Names:
1-
Product Description:
A potent and selective inhibitor of VPS34 (IC50 = 25 nM in vitro); dose-dependently inhibits generation of PtdIns-(3)-p, which is essential to the formation and trafficking of endsomes and autophagosomes, without affecting the ability of class I PI3K to regulate Akt; induces a rapid and pronounced loss of phosphorylation on serum- and glucocorticoid-regulated kinase 3
