BMX-IN-1

Name: BMX-IN-1
Brand: Cayman Chemical
SKU: CBSKU_100663721
Price: 299 GBP
Availability: InStock

Catalogue number:

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CAY19165-5 mg

Supplier:

Cayman Chemical

Size:

5 mg

Product is available in:

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£299.00

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Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.

CAS Number:

1431525-23-3

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C29H24N4O4S

Molecular Weight:

524.6

Alternative Names:

n-[2-methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2h)-yl]phenyl]-2-propenamide, bmx inhibitor 1

Product Description:

An irreversible inhibitor of BMX (IC50 = 8 nM) and BTK (IC50 = 10.4 nM); inhibits the proliferation of Tel-BMX-transformed Ba/F3 prostate cancer cells (GI50 = 25 nM), as well as RV-1, DU-145, PC-3, and VCAP prostate cancer cell lines (GI50s = 2.54, 4.38, 5.37, and 2.46 µM, respectively)