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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
18550-98-6
Alternative Names:
3-(3-pyridinyl)-1-(4-pyridinyl)-2e-propen-1-one
Product Description:
A competitive inhibitor of PFKFB3 (IC50 = 23 µM) that causes a rapid reduction in F2,6BP, glucose uptake, and lactate secretion, resulting in cell cycle arrest in Jurkat cells; markedly reduces intracellular F2,6BP, glucose uptake, and growth of established tumors in mice; also blocks angiogenesis
