10074-G5
Catalogue number:
CAY17408-1 mg
Supplier:
Size:
1 mg
Product is available in:
£46.00
Estimated delivery Tue 26 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
413611-93-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C18H12N4O3
Molecular Weight:
332.3
Alternative Names:
n-
Product Description:
A c-Myc inhibitor that binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 µM), thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (IC50 = 146 µM); cytotoxic to c-Myc-overexpressing cells lines (IC50s = 15.6 and 13.5 µM for Daudi Burkitt lymphoma cells and HL60 promyelocytic leukemia cells, respectively)
